Gut microbiota can have a direct impact on the GI immune system and development of inflammation.2,3,8,9 Metabolic products synthesized by gut microbiota can also have both positive and negative effects on epithelial barrier integrity.8,9
In IBD, some patients have8,9:
Disruption in epithelial barrier integrity can increase microbial penetration and perpetuate the local immune response in patients with IBD.2,4
Thank you for signing up to receive email updates from the Microbiome Consortium. By joining the Microbiome Consortium Professional Community, you will now automatically receive the latest resources and useful information about the gut microbiome.
We appreciate your interest in the gut microbiome and hope you find the information that you receive helpful.